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Research Article| Volume 23, ISSUE 1, P29-35, February 2007

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Effects of Trace Mineral Supplementation, Source, and Growth Implants on Immune Response of Growing and Finishing Feedlot Steers123

  • K.L. Dorton
    Affiliations
    Department of Animal Science, Colorado State University, Fort Collins 80523-1171
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  • T.E. Engle
    Affiliations
    Department of Animal Science, Colorado State University, Fort Collins 80523-1171
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  • R.M. Enns
    Affiliations
    Department of Animal Science, Colorado State University, Fort Collins 80523-1171
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  • J.J. Wagner
    Affiliations
    Department of Animal Science, Colorado State University, Fort Collins 80523-1171
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  • Author Footnotes
    1 Use of trade names in this publication does not imply endorsement by Colorado State University or criticism of similar products not mentioned.
    2 Mention of a proprietary product(s) does not constitute a guarantee or warranty of the product(s) by Colorado State University or the authors and does not imply its approval to the exclusion of other products that may also be suitable.
    3 This research was supported in part by grants from the Colorado State University Agricultural Experiment Station and Zinpro Corp., Eden Prairie, MN.
DOI:https://doi.org/10.1532/S1080-7446(15)30933-5
Effects of Trace Mineral Supplementation, Source, and Growth Implants on Immune Response of Growing and Finishing Feedlot Steers123
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      ABSTRACT

      To determine the effects of growth implants and trace mineral (TM) supplementation and source on immune response, 375 steers (approximately 7 mo of age and 250.0 ± 11.0 kg), stratified by initial body weight, were randomly assigned to 1 of 36 pens that were then randomly assigned to treatments. Treatments consisted of 1) control (no supplemental Cu, Zn, Mn, and Co), 2) inorganic TM (CuSO4, ZnSO4, MnSO4, and CoCO3), and 3) organic TM (iso-amounts of organic Cu, Zn, Mn, and Co). On d 28 post-arrival to the feedlot, steers from 6 pens per treatment received a growth implant containing 200 mg progesterone and 20 mg estradiol benzoate, whereas the other half of the steers within the same treatment (6 pens) did not receive a growth implant. Steers were fed a corn silage-based growing diet for 56 d and were then gradually switched toa high-concentrate finishing diet. At the beginning of the finishing phase, only steers receiving growth implants during the growing phase were reimplanted with 80 mg of trenbolone acetate and 16 mg of estradiol. During the finishing phase, all minerals excluding Zn were fed at NRC recommended concentrations in inorganic form. Treatments during the finishing phase consisted of 1) control (no supplemental Zn), 2) inorganic Zn (30 mg Zn/kg DM from ZnSO4), and 3) organic Zn (iso-amounts of organic Zn). At the end of the growing phase, steers receiving organic TM had greater (P < 0.02) total IgM concentrations than inorganic-supplemented steers, and implanted steers tended (P < 0.07) to have greater IgG antibody titer concentrations specific for pig red blood cells than nonimplanted steers. During the finishing phase, steers supplemented with organic Zn had greater (P = 0.04) ovalbumin antibody titer concentrations than steers supplemented with inorganic TM.Superoxide dismutase activity, interferon gamma concentrations, and antibody titers specific to pig red blood cells and infectious bovine rhinotracheitis virus were unaffectedby TM treatment or growth implants.

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      REFERENCES

        • Bentley O.G.
        • Phillips P.H.
        The effect of low manganese rations upon dairy cattle.
        J. Dairy Sci. 1951; 34: 396
        • Blackmon D.M.
        • Miller W.J.
        • Morton J.D.
        Zinc deficiency in ruminants, occurrence, effects, diagnosis, and treatments.
        Med. (Praha). 1967; 62: 265
        • Cerone S.I.
        • Sansineanea A.S.
        • Streitenberger S.A.
        • Garcia M.C.
        • Auza N.J.
        Cytochrome c oxidase, Cu, Zn-superoxide dismutase, and ceruloplasmin activities in copper deficient bovines.
        Trace Elem. Res. 2000; 73: 268
        • Chandra R.K.
        Nutrition and immunology: From the clinic to cellular biology and back again.
        Proc. Nutr. Soc. 1999; 58: 681
        • Dorton K.L.
        • Engle T.E.
        • Enns R.M.
        Effects of trace mineral supplementation and source, 30 days post-weaning and 28 days post receiving, on performance and health of feeder cattle.
        Asian-australas. J.Anim.Sci. 2006; 19: 1450
        • Dorton K.L.
        • Engle T.E.
        • Hamar D.W.
        • Siciliano P.D.
        • Yemm R.S.
        Effects of copper source and concentration on copper status and immune function in growing and finishing steers.
        Anim. Feed Sci. Technol. 2003; 110: 31
        • Droke E.A.
        • Gengelbach G.P.
        • Spears J.W.
        Influence of level and source (in-organic vs organic) of zinc supplementation on immune function in growing lambs.
        Asian-australas. J. Anim. Sci. 1998; 11: 139
        • Droke E.A.
        • Spears J.W.
        In vitro and in vivo immunological measurements in growing lambs fed diets deficient, marginal or adequate in zinc.
        J. Nutr. Immunol. 1993; 2: 71
        • Droke E.A.
        • Spears J.W.
        • Brown T.T.
        • Qureshi M.A.
        Influence of dietary zinc and dexamethasone on immune responses and resistance to Pasteurella hemolytica challenge in growing lambs.
        Nutr. Res. 1993; 13: 1213
        • Engle T.E.
        • Spears J.W.
        • Brown T.T.
        Effects of dietary phosphorous and trace mineral source on immune function, mineral status, and performance of stressed steers.
        Prof. Anim. Sci. 1999; 15: 238
        • Engle T.E.
        • Spears J.W.
        • Brown T.T.
        • Lloyd K.E.
        Effect of breed (Angus and Simmental) on immune function and response to disease challenge in stressed steers and preweaned calves.
        J. Anim. Sci. 1999; 77: 516
        • Engvall E.
        • Perlmann P.
        Enzymelinked immunosorbent assay, ELISA. 3. Quantitation of specific antibodies by enzyme-labeled anti-immunoglobulin in antigen-coated tubes.
        J. Immunol. 1972; 109: 129
        • Ferket P.R.
        • Qureshi M.A.
        Performance and immunity of heat-stressed broilers fed vitamin- and electrolyte-supplemented drinking water.
        Poult. Sci. 1992; 71: 473
        • George M.H.
        • Nockels C.F.
        • Stanton T.L.
        • Johnson B.
        Effect of source and amount of zinc, copper, manganese, and cobalt fed to stressed heifers on feedlot performance and immune function.
        Prof Anim. Sci. 1997; 13: 84
        • Hambridge K.M.
        • Casey C.E.
        • Krebs N.F.
        Zinc.
        in: Mertz Walter Trace Elements in Human and Animal Nutrition. 5th ed. Academic Press, Inc, London1986: 1
        • Huerta M.
        • Kincaid R.L.
        • Cronrath J.D.
        • Busboom J.
        • Johnson A.B.
        • Swenson C.K.
        Interaction of dietary zinc and growth implants on weight gain, carcass traits and zinc in tissue of growing beef steers and heifers.
        Anim. Feed Sci. Technol. 2002; 95: 15
        • James S.J.
        • Swendseid M.
        • Makinodan T.
        Macrophage-mediated depression of T-cell proliferation in zinc-deficient mice.
        J.Nutr. 1987; 117: 1982
        • Janeway C.A.
        • Travers P.
        Immunobiology: The Immune System in Health and Disease. Current Biology, Ltd. Garland Publ., Inc., New York, NY1996
        • Kegley E.B.
        • Silzell S.A.
        • Kreider D.L.
        • Galloway D.L.
        • Coffey K.P.
        • Hornsby J.A.
        • Hubbell D.S.
        The immune response and performance of calves supplemented with zinc from an organic and inorganic source.
        Prof. Anim. Sci. 2001; 17: 33
        • Kuby J.
        Immunology.
        2nd ed. W. H. Freeman and Company, New York, NY1994
        • Kuhlman G.
        • Roth J.A.
        • Flakoll P.J.
        • Vanderhan M.J.
        • Nissien S.
        Effects of dietary leucine, (-ketoisocaproate and isovalerate on antibody production and lymphocyte blastogenesis in growing lambs.
        J. Nutr. 1988; 118: 1564
        • McDowell L.R.
        Minerals in Animal and Human Nutrition.
        Academic Press, Inc. San Diego, CA. 1992; : 176
        • Mills C.F.
        Biochemical and physiological indicators of minerals status in animals: Copper, cobalt, and zinc.
        J. Anim. Sci. 1987; 65: 1702
        • Murray R.K.
        • Granner D.K.
        • Mayes P.A.
        • Rodwell V.W.
        Harper’s Biochemistry.
        in: 25th ed. McGraw Hill Health Professional Division, New York, NY2000: 135-223
      25. NRC.
        in: Nutrient Requirements of Domestic Animals, Nutrient Requirements of Beef Cattle. 7th. ed. Natl. Acad. Press, Washington, DC1996
        • Paynter D.I.
        The diagnosis of copper insufficiency.
        Copper in Animals and Man. 1987; Vol. I (CRC Press, Boca Raton, FL): 101
        • Rhoads A.R.
        • Stanton T.L.
        • Engle T.E.
        • Kimberling C.V.
        Effects of concentration and source of trace minerals on performance, immunity, mineral and lipid metabolism, and carcass characteristics of beef steers.
        Prof. Anim. Sci. 2003; 19: 150
        • Spears J.W.
        Micronutrients and immune function in cattle.
        Proc. Nutr. Soc. 2000; 59: 1
        • Stabel J.R.
        • Spears J.W.
        Effect of copper on immune function and disease resistance.
        Adv. Exp. Med. Biol. 1989; 258: 243
        • Stabel J.R.
        • Spears J.W.
        • Brown T.T.
        Effect of copper deficiency on tissue, blood characteristics, and immune function of calves challenged with infectious bovine rhinotracheitis virus and Pasteurella hemolytica.
        J. Anim. Sci. 1993; 71: 1247
        • Torre P.M.
        • Harmon R.J.
        • Sordillo L.M.
        • Boissonneault G.A.
        • Hemken R.W.
        • Trammell D.S.
        • Clark T.W.
        Modulation of bovine mononuclear cell proliferation and cytokine production by dietary copper insufficiency.
        J. Nutr. Immunol. 1995; 3: 3
        • Ward J.D.
        • Spears J.W.
        • Kegley E.B.
        Effect of copper level and source (copper lysine vs copper sulfate) on copper status, performance, and immune response in growing steers fed diets with or without supplemental molybdenum and sulfur.
        J. Anim. Sci. 1993; 71: 2748
        • Woolliams C.
        • Suttle N.F.
        • Woolliams J.A.
        • Jones D.G.
        • Wiener G.
        Studies on lambs from lines genetically selected for low and high copper status. 1. Differences in mortality.
        Anim. Prod. 1986; 43: 293
      34. World Health Organization.
        in: Trace elements in human nutrition and health. World Health Org. Publ, Belgium1996

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      DOI: https://doi.org/10.1532/S1080-7446(15)30933-5

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      © 2007 American Registry of Professional Animal Scientists. Published by Elsevier Inc. All rights reserved.

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