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Research Article| Volume 16, ISSUE 2, P111-120, June 2000

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Effects of Pre-Weaning Vitamin E, Selenium, and Copper Supplementation on the Performance, Acute Phase Protein Concentration, and Immune Function of Stressed Beef Calves1

  • Author Footnotes
    2 Present address: Department of Animal Science, North Carolina State University, Box 7621, Raleigh, NC 27695-7621
    C.L. Wright
    Footnotes
    2 Present address: Department of Animal Science, North Carolina State University, Box 7621, Raleigh, NC 27695-7621
    Affiliations
    Department of Animal Science, Kansas State University, Manhattan, KS 66506
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  • Author Footnotes
    3 Present address: Certified Angus Beef, Hylton Heights Rd., Manhattan, KS 66506
    L.R. Corah
    Footnotes
    3 Present address: Certified Angus Beef, Hylton Heights Rd., Manhattan, KS 66506
    Affiliations
    Department of Animal Science, Kansas State University, Manhattan, KS 66506
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  • Author Footnotes
    4 To whom correspondence should be addressed
    G. Stokka
    Footnotes
    4 To whom correspondence should be addressed
    Affiliations
    Department of Animal Science, Kansas State University, Manhattan, KS 66506
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  • F. Blecha
    Affiliations
    Department of Anatomy and Physiology, Kansas State University, Manhattan, KS 66506
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  • Author Footnotes
    2 Present address: Department of Animal Science, North Carolina State University, Box 7621, Raleigh, NC 27695-7621
    3 Present address: Certified Angus Beef, Hylton Heights Rd., Manhattan, KS 66506
    4 To whom correspondence should be addressed
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      Abstract

      Two experiments were conducted to determine the effects of pre-weaning vitamin E, Se, and Cu supplementation on performance and immune response in stressed calves. In Exp. 1, 71 Hereford x Angus calves were individually creep fed: 1) control supplement (CON), 2) control plus 500 IU vitamin E+0.3 mg Se/kg DM (E), 3) control plus 10 mg Cu/kg DM (CU), or 4) a combination of E and CU treatments (ECU). In Exp. 2, 80 Hereford (Angus calves were individually creep fed: 1) control supplement (CON), 2) control plus 0.3 mg Se/kg DM (SE), 3) control plus 500 IU vitamin E+0.3 mg Se/kg DM (LOWE), 4) control plus 1000 IU vitamin E+0.3 mg Se/kg DM (MEDE), or 5) control plus 1500 IU vitamin E+0.3 mg Se/kg DM (HIE). Treatments continued for 49 (Exp. 1) or 53 d (Exp. 2) prior to weaning. At weaning all calves were transported to feedlot facilities. In Exp. 1, vitamin E tended (P<0.09) to improve post-weaning ADG and reduce (P<0.06) plasma haptoglobin (Hp), but had no effect on plasma α-tocopherol. Dietary Cu tended to increase (P<0.01) liver Cu stores, and antibody titers to bovine viral diarrhea (BVD) were greater (P<0.04) at weaning in CU and E calves. In Exp. 2, vitamin E tended to increase serum α-tocopherol (P<0.06) and cortisol (P<0.08). Vitamin E and Se supplementation may improve post-weaning performance and decrease plasma Hp concentrations in stressed calves.

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